Basically as much as someone is willing to pay for it. In the global financial meltdown there's been growing interest in trading pearls. You can get a general idea how to calculate the price of natural pearl Here...
What is the color, weight, shape, the size of your pearl? Can you provide any documentation attesting to the pearl being a Natural Pearl?
If you are thinking about selling it, you might like to consider "offers" and list on The Jewelry Exchange. It's free to list on the Jewelry Exchange.
Best Regards Pete Antique Jewelry Investor Support Team