Hi Susan thank you for writing in. I tried to zoom in on the mark, but still cannot see it clearly. Could you have a look and examine the marks with a magnifying glass or jewelers loupe and see if you can detect the marks or letters?
Cameos have been carved from shell for hundreds of years. Originally a gemstone having layers of different colors like Sardonyx and Cornelian were used. Both of those gemstones rank high on the Mohs Scale of hardness.
Italian cameo were often set in silver like your cameo in the early 20th late 19th century. The leading cameo artist in the 19th century was TOMMASO SAULINI.