Hi Cindy thanks for writing in. Your Mikimoto Clusters of Pearls Pendant sounds beautiful. You mention, the "pearl grapes" are surrounded by silver leaves, I personally prefer white metal with Pearls, I feel it adds to the mystery & allure of white pearls.
Natural Pearls are not the same as Cultured Pearls. Natural Pearls are comprised completely of Nacre, formed without any human intervention and "geographically natural" too, meaning the pearls have not come from a pearl farm. Any pearl stemming from a pearl cultivation farm is a cultured pearl. The Swiss Gemological Institute considers that pearl farming constitutes a human intervention.
The weight of the Pendant will be a significant factor, the quality and condition of the pearls. If you have the original box this will also be big plus. And the Mimikoto signature which is a letter M in a clam shell.